Faculty Information - SEKIYA Hiroshi

（Last updated : 2025-02-11 12:24:34）

SEKIYA Hiroshi
Department Matsuyama University School of Clinical Pharmacy, College of Pharmaceutical Sciences

Position Associate professor

Research Field (Keyword)

Bacteriology (includes mycology)

Publications

1.	2024/04	Article	X-ray structure and mutagenesis analyses of Clostridioides difficile endolysin Ecd09610 glucosaminidase domain (Collaboration)
2.	2023/11	Article	Biochemical Characterizations of the Putative Amidase Endolysin Ecd18980 Catalytic Domain from Clostridioides difficile (Collaboration)
3.	2023/03	Article	Structural and biochemical characterization of Clostridium perfringens pili protein B collagen-binding domains (Collaboration)
4.	2022/08	Article	Biochemical Characterizations of the Putative Endolysin Ecd09610 Catalytic Domain from Clostridioides difficile (Collaboration)
5.	2021/10	Article	Structural and biochemical characterization of the Clostridium perfringens-specific Zn²⁺-dependent amidase endolysin, Psa, catalytic domain (Collaboration)
6.	2021/05	Article	X-ray structures of Clostridium perfringens sortase C with C-terminal cell wall sorting motif of LPST demonstrate role of subsite for substrate-binding and structural variations of catalytic site. (Collaboration)
7.	2021/04	Article	Structural and biochemical characterizations of the novel autolysin Acd24020 from Clostridioides difficile and its full-function catalytic domain as a lytic enzyme. (Collaboration)
8.	2021/03	Article	A Putative Amidase Endolysin Encoded by Clostridium perfringens St13 Exhibits Specific Lytic Activity and Synergizes with the Muramidase Endolysin Psm (Collaboration)
9.	2020/09	Article	Benzoxazole-Based Metal Complexes to Reverse Multidrug Resistance in Bacteria. (Collaboration)
10.	2019/08	Article	Structures of major pilins in Clostridium perfringens demonstrate dynamic conformational change. (Collaboration)
11.	2018/11	Article	Benzoxazole-based Zn(II) and Cu(II) Complexes Overcome Multidrug-resistance in Cancer. (Collaboration)
12.	2018	Article	Synthesis and antimicrobial activity of 2-trifluoroacetonylbenzoxazole ligands and their metal complexes (Collaboration)
13.	2017/11	Article	X-ray structure of Clostridium perfringens sortase B cysteine transpeptidase (Collaboration)
14.	2017/09	Article	Identification of Characteristic Phenolic Constituents in Mousouchiku Extract Used as Food Additives (Collaboration)
15.	2017/04	Article	A Novel Methodology for Synthesis of 1,5,6-Trisubstituted 2(1H)-Pyrazinones of Biological Interest (Collaboration)
16.	2017/01	Article	Structural and biochemical characterization of the Clostridium perfringens autolysin catalytic domain (Collaboration)
17.	2014/12	Other	The visual recognition of parasitic helminths in Japan before the introduction of parasitology from Germany-A preliminary note on the confirmation from Jomon Period onward (Collaboration)
18.	2014/04	Article	X-ray structure of a novel endolysin encoded by episomal phage phiSM101 of Clostridium perfringens (Collaboration)
19.	2011/01	Article	Identification and characterization of a putative endolysin encoded by episomal phage phiSM101 of Clostridium perfringens. (Collaboration)
20.	2010/03	Article	A growing need for international cooperative studies to establish medicinal-plant therapy against obstinate and biohazardous nematodes in the tropical and subtropical areas and in Japan (Collaboration)
21.	2009/08	Article	Gene cloning and characteristics of the RND-type multidrug efflux pump MuxABC-OpmB possessing two RND components in Pseudomonas aeruginosa. (Collaboration)
22.	2009/06	Article	Infections with gastrointestinal parasitic helminths indigenous to Japan and their treatment historically studied in an attempt to control the diseases in countries where they are still rampant: (1) the Jomon to Edo periods. (Collaboration)
23.	2008/12	Article	Construction of the curriculum and lectures for the subject, "History of pharmacy" in Matsuyama University School of Pharmacy. (Collaboration)
24.	2005/11	Article	Gene cloning and properties of the RND-type multidrug efflux pumps MexPQ-OpmE and MexMN-OprM from Pseudomonas aeruginosa. (Collaboration)
25.	2003/09	Article	Functional cloning and characterization of a multidrug efflux pump, MexHI-OpmD, from a Pseudomonas aeruginosa mutant. (Collaboration)
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