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ミトメ ヒデミチ
MITOME Hidemichi
見留 英路 所属 松山大学 薬学部 医療薬学科 職種 准教授 |
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| 言語種別 | 英語 |
| 発行・発表の年月 | 2021/08 |
| 形態種別 | 学術論文 |
| 査読 | 査読有り |
| 標題 | Application of quantative NMR spectroscopy to the quality evaluation of diclofenac gargles as hospital preparations. |
| 執筆形態 | 共著 |
| 掲載誌名 | Chemical & Pharmaceutical Bulletin |
| 掲載区分 | 国外 |
| 出版社・発行元 | The Pharmaceutical Society of Japan |
| 巻・号・頁 | 69(8),pp.721-726 |
| 著者・共著者 | K. Akira, A. Nohara, Y. Utsunomiya, H. Mitome, S. Watanabe, M. Tanaka, A. Tanaka. |
| 概要 | In this paper, we investigated the applicability of quantitative (q)NMR spectroscopy to the quality control of diclofenac gargles as examples of hospital preparations, as it has various merits for the quantitative analysis of mixtures in solutions. Consequently, the gargles were found to be prepared with constant quality, and were stable at room temperature for at least four weeks. qNMR is considered to be potentially useful for the quality control of various hospital preparations because of minimal sample pretreatments, lack of need of calibration curves, and its comprehensive detection abilities. |
| DOI | https://doi.org/10.1248/cpb.c21-00079 |