Faculty Information - NAGAOKA Kenjiro

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（Last updated : 2026-04-01 09:25:03）

NAGAOKA Kenjiro
Department Matsuyama University School of Clinical Pharmacy, College of Pharmaceutical Sciences

Position Associate professor

Educational Background

1.	2003/04～2007/03	Faculty of Pharmaceutical Science, Okayama University, Graduated
2.	2007/04～2009/03	〔Master Course〕, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Completed
3.	2009/03～2012/03	〔Doctorial Course〕, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Completed

Research Field (Keyword)

Pharmaceutical hygiene and biochemistry, Hygiene and public health: including laboratory approach

Publications

1.	2026/01	Article	A Novel Bead-Based Assay for Selective Measurement of Arginase 1 Activity in Human Serum Anal Bioanal Chem (Collaboration)
2.	2025/09	Article	L-citrulline, Arginase Activity, and Nitrate As Potential Nitric Oxide-Related Markers of Subclinical Atherosclerosis in Healthy Middle-Aged Non-smokers: A Cross-Sectional Study Cureus (Collaboration)
3.	2023/07	Article	Filter blot method: A simple method for measuring 3-nitrotyrosine in proteins of atmospheric particulate matter. (Collaboration)
4.	2021/10	Article	Airborne fine particulate matter in Japan induces lipid synthesis and inhibits autophagy in HepG2 cells. (Collaboration)
5.	2021/08	Article	Compromised glutathione synthesis results in high susceptibility to acetaminophen hepatotoxicity in acatalasemic mice. (Collaboration)
6.	2021/05	Article	Possible contribution of hepatocyte secretion to the elevation of plasma exosomal arginase-1 in high-fat diet-fed mice. Life Sci (Collaboration)
7.	2021/03	Article	Role of HO-1 against Saturated Fatty Acid-Induced Oxidative Stress in Hepatocytes Nutrients 13(3),pp.993 (Collaboration)
8.	2019	Article	Detection of 3-Nitrotyrosine in Atmospheric Environments via a High-performance Liquid Chromatography-electrochemical Detector System. J Vis Exp 143,pp.e58371 (Collaboration)
9.	2019	Article	Head cooling during sleep improves sleep quality in the luteal phase in female university students: A randomized crossover-controlled pilot study. PLoS One 14,pp.e0213706 (Collaboration)
10.	2019	Article	Human albumin augmented airway inflammation induced by PM2.5 in NC/Nga mice. (Collaboration)
11.	2018	Article	Association between Occupational Dysfunction and Metabolic Syndrome in Community-Dwelling Japanese Adults in a Cross-Sectional Study: Ibara Study. Int J Environ Res Public Health 15. pii,pp.E2575 (Collaboration)
12.	2018	Article	Association of night eating habits with metabolic syndrome and its components: a longitudinal study. BMC Public Health 18,pp.1366 (Collaboration)
13.	2018	Article	Early obesity leads to increases in hepatic arginase I and related systemic changes in nitric oxide and L-arginine metabolism in mice. J Physiol Biochem 74,pp.9-16 (Collaboration)
14.	2018	Article	Involvement of PM2.5-bound protein and metals in PM2.5-induced allergic airway inflammation in mice. Inhal Toxicol 30,pp.498-508 (Collaboration)
15.	2018	Article	Relationship of particulate matter and ozone with 3-nitrotyrosine in the atmosphere. Environ Pollut 236,pp.948-952 (Collaboration)
16.	2017	Article	Association of arginase I or nitric oxide-related factors with job strain in healthy workers. PLoS One 12,pp.e0175696 (Collaboration)
17.	2017	Article	Effects of exercise training on nitric oxide, blood pressure and antioxidant enzymes. J Clin Biochem Nutr 60,pp.180-186 (Collaboration)
18.	2017	Article	Human lactoferrin induces asthmatic symptoms in NC/Nga mice. Physiol Rep 5,pp.e13365 (Collaboration)
19.	2017	Article	PM2.5-induced airway inflammation and hyperresponsiveness in NC/Nga mice. Environ Toxicol 32,pp.1047-1054 (Collaboration)
20.	2016	Article	Involvement of Xanthine Oxidoreductase-related Oxidative Stress in a Dermatophagoides farinae-induced Asthma Model of NC/Nga Mice. Acta Med Okayama 70,pp.175-182 (Collaboration)
21.	2016	Article	Relationship between serum arginase I and l-arginine or exhaled nitric oxide in asthma. Free Radic Res 50,pp.1165-1172 (Collaboration)
22.	2015	Article	Rebamipide suppresses mite-induced asthmatic responses in NC/Nga mice. Am J Physiol Lung Cell Mol Physiol 309,pp.L872-L878 (Collaboration)
23.	2014	Article	Activation of intestinal human pregnane X receptor protects against azoxymethane/dextran sulfate sodium-induced colon cancer. J Pharmacol Exp Ther 351,pp.559-567 (Collaboration)
24.	2014	Article	Functional characterization of cynomolgus monkey UDP-glucuronosyltransferase 1A9. Eur J Drug Metab Pharmacokinet 39,pp.195-202 (Collaboration)
25.	2014	Article	Hypoxia-inducible factor/MAZ-dependent induction of caveolin-1 regulates colon permeability through suppression of occludin, leading to hypoxia-induced inflammation. Mol Cell Biol 34,pp.3013-3023 (Collaboration)
26.	2014	Article	In vivo effects of the pure aryl hydrocarbon receptor antagonist GNF-351 after oral administration are limited to the gastrointestinal tract. Br J Pharmacol 171,pp.1735-1746 (Collaboration)
27.	2012	Article	The effects of N-glycosylation on the glucuronidation of zidovudine and morphine by UGT2B7 expressed in HEK293 cells. Drug Metab Pharmacokinet 27,pp.388-397 (Collaboration)
28.	2011	Article	Effect of UDP-glucuronosyltransferase 2B15 polymorphism on bisphenol A glucuronidation. Arch Toxicol 85,pp.1373-1381 (Collaboration)
29.	2011	Article	Regio- and stereoselective oxidation of propranolol enantiomers by human CYP2D6, cynomolgus monkey CYP2D17 and marmoset CYP2D19. Chem Biol Interact 189,pp.146-152 (Collaboration)
30.	2010	Article	Comparative study of the oxidation of propranolol enantiomers in hepatic and small intestinal microsomes from cynomolgus and marmoset monkeys. Chem Biol Interact 183,pp.67-78 (Collaboration)
31.	2010	Article	Functional characterization of human and cynomolgus monkey UDP-glucuronosyltransferase 1A1 enzymes. Life Sci 87,pp.261-268 (Collaboration)
32.	2008	Article	Stereoselective glucuronidation of propranolol in human and cynomolgus monkey liver microsomes: role of human hepatic UDP-glucuronosyltransferase isoforms, UGT1A9, UGT2B4 and UGT2B7. Pharmacology 82,pp.293-303 (Collaboration)
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