Faculty Information - SAWAMOTO Atsushi

E-mail Address

Educational Background

Work experience /Academic appointments

Publications

（Last updated : 2025-01-09 09:52:58）

SAWAMOTO Atsushi
Department Matsuyama University School of Clinical Pharmacy, College of Pharmaceutical Sciences

Position Associate professor

E-mail Address

Educational Background

1.	2008/04～2014/03	Faculty of Pharmaceutical Science, Matsuyama University, Graduated,
2.	2014/04～2018/03	〔Doctoral course〕, Clinical Pharmacy, Matsuyama University, Completed,

Work experience /Academic appointments

1.	2021/04～2022/09	Lecturer
2.	2022/10～	Associate Professor

Publications

1.	2025/02	Article	Reduction in MCP-1 production in preadipocytes is mediated by PPARγ activation and JNK/SIRT1 signaling (Collaboration)
2.	2024/11	Article	Anti-Inflammatory and Neurotrophic Factor Production Effects of 3,5,6,7,8,3′,4′-Heptamethoxyflavone in the Hippocampus of Lipopolysaccharide-Induced Inflammation Model Mice (Collaboration)
3.	2024/10	Article	Cloperastine Reduces IL-6 Expression via Akt/GSK3/Nrf2 Signaling in Monocytes/Macrophages and Ameliorates Symptoms in a Mouse Sepsis Model Induced by Lipopolysaccharide (Collaboration)
4.	2024/10	Article	Benproperine reduces IL-6 levels via Akt signaling in monocyte/macrophage-lineage cells and reduces the mortality of mouse sepsis model induced by lipopolysaccharide (Collaboration)
5.	2024/03	Article	Tipepidine activates AMPK and improves adipose tissue fibrosis and glucose intolerance in high-fat diet-induced obese mice (Collaboration)
6.	2024/03	Article	Sulconazole induces pyroptosis promoted by interferon- γ in monocyte/macrophage lineage cells (Collaboration)
7.	2023/03	Article	Effects of Citrus kawachiensis Peel in Frailty-like Model Mice Induced by Low Protein Nutrition Disorders (Collaboration)
8.	2023/02	Article	N-Caffeoyltryptophan enhances adipogenic differentiation in preadipocytes and improves glucose tolerance in mice (Collaboration)
9.	2022/08	Article	Ibudilast Reduces IL-6 Levels and Ameliorates Symptoms in Lipopolysaccharide-Induced Sepsis Mice (Collaboration)
10.	2022/05	Article	Beneficial effects of Citrus kawachiensis peel on neurogenesis in the hippocampus and gut microbiota changes in a chronic unpredictable mild stress mouse model (Collaboration)
11.	2021/12	Article	Neuroprotective and Anti-Microglial Activation Effects of Tocotrienols in Brains of Lipopolysaccharide-Induced Inflammatory Model Mice (Collaboration)
12.	2021/01	Article	T-Cell Activation-Inhibitory Assay to Screen Caloric Restriction Mimetics Drugs for Drug Repositioning (Collaboration)
13.	2021/01	Article	Isolation and Characterization of Neuroprotective Components from Citrus Peel and Their Application as Functional Food (Collaboration)
14.	2020/10	Article	Cynandione A induces adipogenesis and beige adipocyte-related phenotype in 3T3-L1 cells (Collaboration)
15.	2020/03	Article	Citrus Auraptene Induces Expression of Brain-Derived Neurotrophic Factor in Neuro2a Cells (Collaboration)
16.	2019/12	Article	Heptamethoxyflavone inhibits adipogenesis via enhancing PKA signaling (Collaboration)
17.	2019/12	Article	T-cell activation-inhibitory assay: a proposed novel method for screening caloric restriction mimetics (Collaboration)
18.	2019/12	Article	Citrus Auraptene Induces Glial Cell Line-Derived Neurotrophic Factor in C6 Cells (Collaboration)
19.	2019/08	Article	Citrus flavonoid 3,5,6,7,8,3',4'-heptamethoxyflavone induces BDNF via cAMP/ERK/CREB signaling and reduces phosphodiesterase activity in C6 cells (Collaboration)
20.	2019/04	Article	Continual Treatment with the Peels of Citrus kawachiensis (Kawachi Bankan) Protects against Dopaminergic Neuronal Cell Death in a Lipopolysaccharide-Induced Model of Parkinson's Disease (Collaboration)
21.	2019/04	Article	Effects of Carbazole Derivatives on Neurite Outgrowth and Hydrogen Peroxide-Induced Cytotoxicity in Neuro2a Cells (Collaboration)
22.	2019/03	Article	Hydrolysable tannins, gallic acid, and ellagic acid in walnut reduced 3-(4, 5-Dimethylthiazol-2-yl)-2, 5-Diphenyltetrazolium bromide (MTT) reduction in T-Cells cultured from the spleen of mice. (Collaboration)
23.	2019/02	Article	Auraptene/Naringin-Rich Fruit Juice of Citrus kawachiensis (Kawachi Bankan) Prevents Ischemia-Induced Neuronal Cell Death in Mouse Brain through Anti-Inflammatory Responses (Collaboration)
24.	2018/08	Article	Inhibitory Effects of Auraptene and Naringin on Astroglial Activation, Tau Hyperphosphorylation, and Suppression of Neurogenesis in the Hippocampus of Streptozotocin-Induced Hyperglycemic Mice (Collaboration)
25.	2018/08	Article	Suppressive effects of the peel of Citrus kawachiensis (Kawachi Bankan) on astroglial activation, tau phosphorylation, and inhibition of neurogenesis in the hippocampus of type 2 diabetic db/db mice (Collaboration)
26.	2018/07	Article	Neuroprotective effect of Citrus kawachiensis (Kawachi Bankan) peels, a rich source of naringin, against global cerebral ischemia/reperfusion injury in mice (Collaboration)
27.	2018/05	Article	The peel of Citrus kawachiensis (kawachi bankan) ameliorates microglial activation, tau hyper-phosphorylation, and suppression of neurogenesis in the hippocampus of senescence-accelerated mice (Collaboration)
28.	2018/01	Article	Sansoninto as evidence-based remedial medicine for depression-like behavior (Collaboration)
29.	2017/10	Article	3,5,6,7,8,3',4'-Heptamethoxyflavone Ameliorates Depressive-Like Behavior and Hippocampal Neurochemical Changes in Chronic Unpredictable Mild Stressed Mice by Regulating the Brain-Derived Neurotrophic Factor: Requirement for ERK Activation (Collaboration)
30.	2017/02	Article	Permeation of Polymethoxyflavones into the Mouse Brain and Their Effect on MK-801-Induced Locomotive Hyperactivity (Collaboration)
31.	2016/10	Article	Auraptene and Other Prenyloxyphenylpropanoids Suppress Microglial Activation and Dopaminergic Neuronal Cell Death in a Lipopolysaccharide-Induced Model of Parkinson’s Disease (Collaboration)
32.	2016/04	Article	3,5,6,7,8,3',4'-Heptamethoxyflavone, a Citrus Flavonoid, Ameliorates Corticosterone-Induced Depression-like Behavior and Restores Brain-Derived Neurotrophic Factor Expression, Neurogenesis, and Neuroplasticity in the Hippocampus (Collaboration)
33.	2015/04	Article	Edaravone enhances brain-derived neurotrophic factor production in the ischemic mouse brain (Collaboration)
34.	2014/05	Article	3,5,6,7,8,3',4'-Heptamethoxyflavone, a citrus flavonoid, on protection against memory impairment and neuronal cell death in a global cerebral ischemia mouse model (Collaboration)
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