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MITOME Hidemichi
Department Matsuyama University School of Clinical Pharmacy, College of Pharmaceutical Sciences Position Associate professor |
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| Language | English |
| Publication Date | 2021/08 |
| Type | |
| Peer Review | With peer review |
| Title | Application of quantative NMR spectroscopy to the quality evaluation of diclofenac gargles as hospital preparations. |
| Contribution Type | |
| Journal | Chemical & Pharmaceutical Bulletin |
| Journal Type | Another Country |
| Publisher | The Pharmaceutical Society of Japan |
| Volume, Issue, Pages | 69(8),pp.721-726 |
| Author and coauthor | K. Akira, A. Nohara, Y. Utsunomiya, H. Mitome, S. Watanabe, M. Tanaka, A. Tanaka. |
| Details | In this paper, we investigated the applicability of quantitative (q)NMR spectroscopy to the quality control of diclofenac gargles as examples of hospital preparations, as it has various merits for the quantitative analysis of mixtures in solutions. Consequently, the gargles were found to be prepared with constant quality, and were stable at room temperature for at least four weeks. qNMR is considered to be potentially useful for the quality control of various hospital preparations because of minimal sample pretreatments, lack of need of calibration curves, and its comprehensive detection abilities. |