ミトメ　ヒデミチ   MITOME Hidemichi   見留　英路    所属   松山大学  薬学部 医療薬学科    職種   准教授
言語種別	英語
発行・発表の年月	2016/04
形態種別	学術論文
査読	査読有り
標題	Amitorines A and B, Nitrogenous Diterpene Metabolites of Theonella swinhoei: Isolation, Structure Elucidation, and Asymmetric Synthesis
執筆形態	共著
掲載誌名	Journal of Natural Products
掲載区分	国外
出版社・発行元	American Chemical Society-American Society of Pharmacognosy
巻・号・頁	79(4),pp.996-1004
著者・共著者	Koichiro Ota, Yukiko Hamamoto, Wakiko Eda, Kenta Tamura, Akiyoshi Sawada, Ayako Hoshino, Hidemichi Mitome, Kazuo Kamaike, Hiroaki Miyaoka
概要	Two new nitrogenous prenylbisabolanes never before found in Lithistid sponges have been isolated from Theonella swinhoei. These new diterpenes, named amitorine A (1) and amitorine B (2), contg. a prenylbisabolane skeleton have been characterized by spectroscopic analyses, and the relative and abs. configurations of 1 and 2 were detd. by asym. synthesis of both diastereomers via the common bicyclic lactone 6 intermediate.
DOI	https://doi.org/10.1021/acs.jnatprod.5b01069