ミトメ　ヒデミチ   MITOME Hidemichi   見留　英路    所属   松山大学  薬学部 医療薬学科    職種   准教授
言語種別	英語
発行・発表の年月	2013/05
形態種別	学術論文
査読	査読有り
標題	An efficient laboratory-scale preparative method for [1-13C]glycocholic acid
執筆形態	共著
掲載誌名	Journal of Labelled Compounds and Radiopharmaceuticals
巻・号・頁	56(11),pp.587-588
著者・共著者	Hidemichi Mitome, Naoko Tokumasu, Yusuke Tando, Teruo Nakamura, Kazuki Akira
概要	A breath test using [1-13C]glycocholic acid as a substrate is a potential diagnostic method for small intestinal bacterial overgrowth syndrome. [1-13C]Glycocholic acid has been thus synthesized in an excellent yield from [1-13C]glycine Et ester hydrochloride in a one-pot reaction. This method is suitable for the prepn. of the labeled compd. on a lab. scale, which helps to perform extensive clin. studies of the breath test.